Pharmacodynamics and biodistribution of [195mPt]cisplatin(CISSPECT®) in head and neck squamous cell carcinoma

Abstract Background Cisplatin- based chemoradiotherapy is a crucial pillar in the treatment of HNSCC. The use of cisplatin comes with high toxicity rates as 35% of patients cannot sustain the planned dose while response is unpredictable. Unfortunately, there are no clinically applicable biomarkers t...

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Autors principals:	Reinout H. de Roest, Marijke Stigter van Walsum, Karlijn van der Schilden, Ruud H. Brakenhoff
Format:	Artigo
Idioma:	Inglês
Publicat:	SpringerOpen 2024-03-01
Col·lecció:	EJNMMI Research
Matèries:	Head and neck squamous cell carcinoma Cisplatin [195m]Platinum Cisspect
Accés en línia:	https://doi.org/10.1186/s13550-024-01082-w
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