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Human Prolactin Point Mutations and Their Projected Effect on Vasoinhibin Generation and Vasoinhibin-Related Diseases

BackgroundA dysregulation of the generation of vasoinhibin hormones by proteolytic cleavage of prolactin (PRL) has been brought into context with diabetic retinopathy, retinopathy of prematurity, preeclampsia, pregnancy-induced hypertension, and peripartum cardiomyopathy. Factors governing vasoinhib...

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Autors principals: Jakob Triebel, Christin J. Friedrich, Andreas Leuchs, Gonzalo Martínez de la Escalera, Carmen Clapp, Thomas Bertsch
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017-11-01
Col·lecció:Frontiers in Endocrinology
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Accés en línia:http://journal.frontiersin.org/article/10.3389/fendo.2017.00294/full
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