Mechanistic insights into novel cyano-pyrimidine pendant chalcone derivatives as LSD1 inhibitors by docking, ADMET, MM/GBSA, and molecular dynamics simulation

Cancer presents a formidable and complex foe, standing as one of the foremost contributors to disease-related fatalities across the globe. According to data from the Global Cancer Observatory (GLOBOCAN), projections indicate a staggering 28.4 million cases of cancer, encompassing both new diagnoses...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Amisha Gupta, Darakhshan Parveen, Faizul Azam, M. Shaquiquzzaman, Mymoona Akhter, Mariusz Jaremko, Abdul-Hamid Emwas, Mohammad Ahmed Khan, Suhel Parvez, Suruchi Khanna, Rituparna Palit, Umar Jahangir, M. Mumtaz Alam
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2025-03-01
Ráidu:	Biochemistry and Biophysics Reports
Fáttát:	Cancer LSD1 Chalcone Cyano-pyrimidine Molecular docking Molecular dynamics
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S240558082500024X
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!