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Refractory Neuropathic Pain in the Head and Neck: Neuroanatomical and Clinical Significance of the Cervicotrigeminal Complex

Refractory neuropathic pain of the head and neck remains a major clinical challenge, particularly when mediated through the cervicotrigeminal complex (CTC), a unique anatomical hub integrating trigeminal and upper cervical nociceptive inputs. This narrative review synthesizes neuroanatomical, pathop...

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Hlavní autoři: Marina Raguž, Marko Tarle, Koraljka Hat, Ivan Salarić, Petar Marčinković, Ivana Bičanić, Elvira Lazić Mosler, Ivica Lukšić, Tonko Marinović, Darko Chudy
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2025-09-01
Edice:Life
Témata:
cervicotrigeminal complex
trigeminocervical convergence
refractory neuropathic pain
central sensitization
neuromodulation
head and neck disorders
On-line přístup:https://www.mdpi.com/2075-1729/15/9/1457
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