SIAE Rare Variants in Juvenile Idiopathic Arthritis and Primary Antibody Deficiencies
Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. In humans, studies of rare heterozygous loss-of-function mutations in SIAE gene in common autoimmune diseas...
Gardado en:
| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Acceso en liña: | http://dx.doi.org/10.1155/2017/1514294 |
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