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The role of the mitochondrial outer membrane protein SLC25A46 in mitochondrial fission and fusion

The mitochondrial outer membrane protein SLC25A46 localizes to mitochondrial fusion and fission sites, and loss of function alters mitochondrial morphology and oligomerization states of MFN2 and OPA1. Mutations in SLC25A46 underlie a wide spectrum of neurodegenerative diseases associated with altera...

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Autors principals: Jana Schuettpelz, Alexandre Janer, Hana Antonicka, Eric A Shoubridge
Format: Artigo
Idioma:Inglês
Publicat: Life Science Alliance LLC 2023-06-01
Col·lecció:Life Science Alliance
Accés en línia:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202301914
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