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Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin

Recent successes of adeno-associated virus (AAV)âbased gene therapy have created a demand for large-scale AAV vector manufacturing and purification techniques for use in clinical trials and beyond. During the development of purification protocols for rh.10, hu.37, AAV8, rh.64R1, AAV3B, and AAV9 vect...

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Autors principals: Qiang Wang, Martin Lock, Andrew J Prongay, Mauricio R Alvira, Boris Petkov, James M Wilson
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015-01-01
Col·lecció:Molecular Therapy: Methods & Clinical Development
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2329050116300523
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