DNA methylation profile in chronic myelomonocytic leukemia associates with distinct clinical, biological and genetic features

Chromosomal abnormalities are detected in 20–30% of patients with chronic myelomonocytic leukemia (CMML) and correlate with prognosis. On the mutation level, disruptive alterations are particularly frequent in chromatin regulatory genes. However, little is known about the consequential alterations i...

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Detalhes bibliográficos

Principais autores:	Laura Palomo, Roberto Malinverni, Marta Cabezón, Blanca Xicoy, Montserrat Arnan, Rosa Coll, Helena Pomares, Olga García, Francisco Fuster-Tormo, Javier Grau, Evarist Feliu, Francesc Solé, Marcus Buschbeck, Lurdes Zamora
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2018-01-01
Colecção:	Epigenetics
Assuntos:	chronic myelomonocytic leukemia dna methylation hypermethylation prognosis tet2
Acesso em linha:	http://dx.doi.org/10.1080/15592294.2017.1405199
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