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Quantification of Etoricoxib in Low Plasma Volume by UPLC-PDA and Application to Preclinical Pharmacokinetic Study

An ultra-performance liquid chromatography with photodiode array (UPLC-PDA) UV detection method was developed here for the first time for simple, rapid, selective and sensitive quantification of the commonly prescribed selective cyclooxygenase-2 (COX-2) inhibitor etoricoxib in low plasma volumes (50...

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Principais autores: Sapir Ifrah, Daniel Porat, Mordechai Deutsch, Arik Dahan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-04-01
coleção:Pharmaceuticals
Assuntos:
liquid–liquid extraction
COX-2 inhibitor
etoricoxib
trazodone
analytical method
drug determination
Acesso em linha:https://www.mdpi.com/1424-8247/17/4/507
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