Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function mutations

Background Apolipoprotein C-III (apoC-III) is a regulator of triglyceride (TG) metabolism, and due to its association with risk of cardiovascular disease, is an emergent target for pharmacological intervention. The impact of substantially lowering apoC-III on lipoprotein metabolism is not clear.Meth...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Marja-Riitta Taskinen, Elias Björnson, Niina Matikainen, Sanni Söderlund, Joel Rämö, Mari-Mia Ainola, Antti Hakkarainen, Carina Sihlbom, Annika Thorsell, Linda Andersson, Per-Olof Bergh, Marcus Henricsson, Stefano Romeo, Martin Adiels, Samuli Ripatti, Markku Laakso, Chris J. Packard, Jan Borén
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical investigation 2022-10-01
Serie:	JCI Insight
Soggetti:	Metabolism
Accesso online:	https://doi.org/10.1172/jci.insight.160607
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!