AtrR Is an Essential Determinant of Azole Resistance in <named-content content-type="genus-species">Aspergillus fumigatus</named-content>

ABSTRACT Aspergillosis associated with azole-resistant Aspergillus fumigatus has a mortality rate that can approach 90% in certain patient populations. The best-understood avenue for azole resistance involves changes in the cyp51A gene that encodes the target of azole drugs, lanosterol α-14 demethyl...

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Ngā kaituhi matua:	Sanjoy Paul, Mark Stamnes, Grace Heredge Thomas, Hong Liu, Daisuke Hagiwara, Katsuya Gomi, Scott G. Filler, W. Scott Moye-Rowley
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	American Society for Microbiology 2019-04-01
Rangatū:	mBio
Ngā marau:	ABC transporters antifungal resistance Aspergillus fumigatus molecular genetics transcriptional regulation
Urunga tuihono:	https://journals.asm.org/doi/10.1128/mBio.02563-18
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!