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Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases

Ectonucleoside triphosphate diphosphohydrolases (NTPDases) are ectoenzymes that play an important role in the hydrolysis of nucleoside triphosphate and diphosphate to nucleoside monophosphate. NTPDase1, -2, -3 and -8 are the membrane bound members of this enzyme family that are responsible for regul...

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書誌詳細
主要な著者: Saira Afzal, Mariya al-Rashida, Abdul Hameed, Julie Pelletier, Jean Sévigny, Jamshed Iqbal
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020-11-01
シリーズ:Frontiers in Pharmacology
主題:
オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2020.585876/full
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