Large-scale template-based structural modeling of T-cell receptors with known antigen specificity reveals complementarity features

IntroductionT-cell receptor (TCR) recognition of foreign peptides presented by the major histocompatibility complex (MHC) initiates the adaptive immune response against pathogens. While a large number of TCR sequences specific to different antigenic peptides are known to date, the structural data de...

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Principais autores:	Dmitrii S. Shcherbinin, Vadim K. Karnaukhov, Ivan V. Zvyagin, Dmitriy M. Chudakov, Mikhail Shugay
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-08-01
coleção:	Frontiers in Immunology
Assuntos:	T-cell receptor antigen recognition TCR-peptide-MHC complex structural modeling database
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1224969/full
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