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Enzymatic synthesis of mono- and trifluorinated alanine enantiomers expands the scope of fluorine biocatalysis

Abstract Fluorinated amino acids serve as an entry point for establishing new-to-Nature chemistries in biological systems, and novel methods are needed for the selective synthesis of these building blocks. In this study, we focused on the enzymatic synthesis of fluorinated alanine enantiomers to exp...

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Bibliografiske detaljer
Principais autores: Manuel Nieto-Domínguez, Aboubakar Sako, Kasper Enemark-Rasmussen, Charlotte Held Gotfredsen, Daniela Rago, Pablo I. Nikel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-05-01
Serier:Communications Chemistry
Online adgang:https://doi.org/10.1038/s42004-024-01188-1
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