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Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis.

<h4>Background</h4>Immucillins ImmA (IA), ImmH (IH) and SerMe-ImmH (SMIH) are synthetic deazapurine nucleoside analogues that inhibit Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis multiplication in vitro without macrophage toxicity. Immucillins are compared to the Glucantime stand...

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Principais autores: Elisangela Oliveira Freitas, Dirlei Nico, Marcus Vinícius Alves-Silva, Alexandre Morrot, Keith Clinch, Gary B Evans, Peter C Tyler, Vern L Schramm, Clarisa B Palatnik-de-Sousa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2015-12-01
Serier:PLoS Neglected Tropical Diseases
Online adgang:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004297&type=printable
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