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SEDS glycosyltransferases in E. faecalis are upregulated by the CroS/R two-component system to enhance peptidoglycan synthesis during cell wall stress

ABSTRACT Enterococci are commensals of the intestinal tract that are intrinsically resistant to cephalosporins, antibiotics that inhibit peptidoglycan synthesis. Prior treatment with cephalosporins is a risk factor for acquiring an enterococcal infection. We previously showed that FtsW, a SEDS (shap...

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Autores principales: Madison E. Nelson, Dušanka Djorić, Miryah E. Henriksen-Hadlock, Christopher J. Kristich
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2025-12-01
Colección:mSphere
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Acceso en línea:https://journals.asm.org/doi/10.1128/msphere.00528-25
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