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A Network-Centric Framework for the Evaluation of Mutual Exclusivity Tests on Cancer Drivers

One of the key concepts employed in cancer driver gene identification is that of mutual exclusivity (ME); a driver mutation is less likely to occur in case of an earlier mutation that has common functionality in the same molecular pathway. Several ME tests have been proposed recently, however the cu...

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Principais autores: Rafsan Ahmed, Cesim Erten, Aissa Houdjedj, Hilal Kazan, Cansu Yalcin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-11-01
coleção:Frontiers in Genetics
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2021.746495/full
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