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A Function for the hnRNP A1/A2 Proteins in Transcription Elongation.

The hnRNP A1 and A2 proteins regulate processes such as alternative pre-mRNA splicing and mRNA stability. Here, we report that a reduction in the levels of hnRNP A1 and A2 by RNA interference or their cytoplasmic retention by osmotic stress drastically increases the transcription of a reporter gene....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Bruno Lemieux, Marco Blanchette, Anne Monette, Andrew J Mouland, Raymund J Wellinger, Benoit Chabot
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2015-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC4444011?pdf=render
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