Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule

Background: Enalapril is often used in the treatment of cardiovascular diseases. Clinical data suggest that the urinary excretion of enalaprilat, the active metabolite of enalapril, is mediated by renal transporters. We aimed to identify enalaprilat specificity for renal proximal tubular transporter...

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主要な著者:	Nori J. L. Smeets, Carlijn H. C. Litjens, Jeroen J. M. W. van den Heuvel, Hedwig van Hove, Petra van den Broek, Frans G. M. Russel, Jan B. Koenderink, Saskia N. de Wildt
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2020-09-01
シリーズ:	Pharmaceutics
主題:	enalapril enalaprilat drug transporters proximal tubule cell
オンライン･アクセス:	https://www.mdpi.com/1999-4923/12/10/935
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