STARD4 suppresses tumorigenesis and attenuates enzalutamide resistance via lipid metabolic reprogramming and AR stabilization in prostate cancer

Abstract Background Prostate cancer (PCa) is a globally prevalent malignancy in males and is imposing an increasing epidemiological burden. The androgen receptor (AR) signalling axis is fundamentally implicated in PCa tumorigenesis and disease progression. Although androgen deprivation therapy (ADT)...

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Principais autores:	Yi Zhang, Xi Wang, Jiuyi Wang, Ke Ma, Lei Jia, Bo Liu, Xianglin Yuan, Qiang Li, Qinzhang Wang, Qinyu Li, Kai Zeng
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2025-12-01
סדרה:	Journal of Experimental & Clinical Cancer Research
נושאים:	Prostate cancer STARD4 Lipid metabolism Androgen receptor Enzalutamide resistance
גישה מקוונת:	https://doi.org/10.1186/s13046-025-03600-7
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!