Hepatic Expression of the Serine Palmitoyltransferase Subunit Sptlc2 Reduces Lipid Droplets in the Liver by Activating VLDL Secretion

Objective Ceramide is a signaling molecule that contributes to insulin resistance and hepatosteatosis. In the present study, we activated de novo ceramide synthesis by inducing the hepatic expression of Sptlc2 to investigate the role of ceramide in glucose and lipid metabolism. Methods We first...

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מידע ביבליוגרפי

Principais autores:	Goon-Tae Kim, Su-Jung Kim, Si-Hyun Park, Dongyup Lee, Tae-Sik Park
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	The Korean Society of Lipid and Atherosclerosis 2020-05-01
סדרה:	Journal of Lipid and Atherosclerosis
נושאים:	fatty liver lipoprotein serine palmitoyltransferase ceramides gluconeogenesis
גישה מקוונת:	https://www.e-jla.org/search.php?where=aview&id=10.12997/jla.2020.9.2.291&code=9992JLA&vmode=FULL
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