Silencing of NOTCH3 Signaling in Meniscus Smooth Muscle Cells Inhibits Fibrosis and Exacerbates Degeneration in a HEYL‐Dependent Manner

Abstract The mechanisms of meniscus fibrosis and novel ways to enhance fibrosis is unclear. This work reveals human meniscus fibrosis initiated at E24 weeks. Smooth muscle cell cluster is identified in embryonic meniscus, and the combined analysis with previous data suggests smooth muscle cell in em...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Hao Sun, Fangzhou Liu, Zhencan Lin, Zongrui Jiang, Xingzhao Wen, Jie Xu, Zhiqi Zhang, Ruofan Ma
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2023-06-01
Serija:	Advanced Science
Teme:	meniscus degeneration meniscus fibrosis NOTCH3 smooth muscle cell
Online dostop:	https://doi.org/10.1002/advs.202207020
Oznake:	Označite Brez oznak, prvi označite!