Potential Targets to Mitigate Trauma- or Sepsis-Induced Immune Suppression

In sepsis and trauma, pathogens and injured tissue provoke a systemic inflammatory reaction which can lead to overwhelming inflammation. Concurrent with the innate hyperinflammatory response is adaptive immune suppression that can become chronic. A current key issue today is that patients who underg...

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Detalhes bibliográficos

Principais autores:	Christian B. Bergmann, Nadine Beckmann, Christen E. Salyer, Marc Hanschen, Peter A. Crisologo, Charles C. Caldwell
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-02-01
coleção:	Frontiers in Immunology
Assuntos:	IL-10 transforming growth factor β thymic stromal lymphopoietin immunosuppression chronic critical illness
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.622601/full
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