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In vitro and in vivo effects of Pelargonium sidoides DC. root extract EPs® 7630 and selected constituents against SARS-CoV-2 B.1, Delta AY.4/AY.117 and Omicron BA.2

The occurrence of immune-evasive SARS-CoV-2 strains emphasizes the importance to search for broad-acting antiviral compounds. Our previous in vitro study showed that Pelargonium sidoides DC. root extract EPs® 7630 has combined antiviral and immunomodulatory properties in SARS-CoV-2-infected human lu...

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Principais autores: Jackson Emanuel, Jan Papies, Celine Galander, Julia M. Adler, Nicolas Heinemann, Kathrin Eschke, Sophie Merz, Hannah Pischon, Ruben Rose, Andi Krumbholz, Žarko Kulić, Martin D. Lehner, Jakob Trimpert, Marcel A. Müller
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-07-01
coleção:Frontiers in Pharmacology
Assuntos:
SARS-CoV-2
coronavirus
Pelargonium sidoides
EPs 7630
drug repurposing
immune modulation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2023.1214351/full
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