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Aerosol Inhalation Delivery of Ceftriaxone in Mice: Generation Procedure, Pharmacokinetics, and Therapeutic Outcome

Aerosol inhalation delivery of ceftriaxone in mice was investigated. An ultrasonic nebulizer within the ranges of mean particle diameter 0.5–1.5 μm and mass concentration 0.01–0.6 μg/cm<sup>3</sup> was used in inhalation experiments. Pharmacokinetic measurements were carried out using a nose-only ch...

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Wedi'i Gadw mewn:
Prif Awduron: Sergey V. Valiulin, Andrei A. Onischuk, Anatoly M. Baklanov, Sergey V. An’kov, Sergey N. Dubtsov, Alexander A. Alekseev, Nikolay N. Shkil, Ekaterina V. Nefedova, Maria E. Plokhotnichenko, Tatyana G. Tolstikova, Arseniy M. Dolgov, Galina G. Dultseva
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2022-09-01
Cyfres:Antibiotics
Pynciau:
antibacterial agents
ceftriaxone
inhalation
mice
survival rate
<i>Klebsiella</i>
Mynediad Ar-lein:https://www.mdpi.com/2079-6382/11/10/1305
Tagiau: Ychwanegu Tag
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