Hydrophilic Liquid Chromatography versus Reversed-Phase Liquid Chromatography in the Absence and the Presence of 1-Hexyl-3-methylimidazolium Chloride for the Analysis of Basic Compounds

In reversed-phase liquid chromatography (RPLC), positively charged basic compounds yield broad and asymmetric peaks, as a result of ionic interactions with free silanols that remain on conventional silica-based columns. Diverse solutions have been proposed to mask the silanophilic activity, which is...

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Principais autores:	Ester Peris-García, Raquel Burgos-Gil, María Celia García-Alvarez-Coque, María José Ruiz-Angel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-05-01
coleção:	Separations
Assuntos:	hydrophilic interaction liquid chromatography reversed-phase liquid chromatography ionic liquids basic compounds chromatographic behavior
Acesso em linha:	https://www.mdpi.com/2297-8739/7/2/30
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