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Cannabidiol triggers fatty acids β-oxidation mediated by Stat2 to facilitate intestinal stem cells regeneration post radiation

Abstract The development of compounds triggering intestinal stem cells (ISCs) proliferation represents a promising strategy to alleviate irradiation (IR)-induced gastrointestinal syndrome. Here, cannabidiol (CBD)-a nonpsychotomimetic phytocannabinoid derived from the Cannabis sativa plant-was found...

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Principais autores: Zebin Liao, Congshu Huang, Liangliang Zhang, Changkun Hu, Zekun Wu, Zhijie Bai, Gaofu Li, Lei Zhou, Ningning Wang, Chaoji Huangfu, Zhexin Ni, Pan Shen, Wei Zhou, Yue Gao
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2026-05-01
Serija:Experimental and Molecular Medicine
Online dostop:https://doi.org/10.1038/s12276-026-01711-5
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