Impact of immune microenvironment on immune checkpoint inhibitor response in HER2-overexpressing urothelial carcinoma

Abstract Background The biological interaction between human epidermal growth factor receptor 2 (HER2) overexpression and the tumor immune microenvironment (TIME) in urothelial carcinoma (UC) has not been comprehensively elucidated, which limits the rational integration of HER2-targeted therapies wi...

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Bibliografski detalji

Glavni autori:	Ruiyang Xia, Meiling Wang, Ning Wang, Yinxu Zhang, Jiahe Zhao, Zhen Wang, Wei Wang, Shuangyan Zheng, Kunxian Huang, Jianshu Dong, Bona Liu, Cheng Du
Format:	Artigo
Jezik:	Inglês
Izdano:	Springer 2026-04-01
Serija:	Discover Oncology
Teme:	Urothelial carcinoma (UC) Human epidermal growth factor receptor2 (HER2) Immune checkpoint inhibitor (ICI) Disitamab vedotin (RC48)
Online pristup:	https://doi.org/10.1007/s12672-026-04974-6
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