Multi-omics-based decoding of circulating biomarkers in amyotrophic lateral sclerosis and risks in environmental toxins

Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the interplay of genetic and environmental factors, and currently, there there is a lack of effective diagnostic or therapeutic strategies available. This study aims to identify circulating...

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Bibliographic Details

Main Authors:	Lei Xu, Bin Huang, Yaqiu Zhou, Xiaolin Liao, Ting Chen, Hongping He
Format:	Artigo
Language:	Inglês
Published:	BMC 2025-11-01
Series:	BMC Pharmacology and Toxicology
Subjects:	Amyotrophic lateral sclerosis Multi-omics Integrated machine learning Reverse network toxicology
Online Access:	https://doi.org/10.1186/s40360-025-01024-9
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