More epigenetic hits than meets the eye: microRNAs and genes associated with the tumorigenesis of retinoblastoma
Retinoblastoma (RB), a childhood neoplasia of the retinoblasts, can occur unilaterally or bilaterally, with one or multiple foci per eye. RB is associated with somatic loss-of-function of both alleles of the tumor suppressor gene RB1. Hereditary forms emerge due to germline loss-of-function mutation...
Sábháilte in:
| Príomhchruthaitheoirí: | , , |
|---|---|
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Frontiers Media S.A.
2012-12-01
|
| Sraith: | Frontiers in Genetics |
| Ábhair: | |
| Rochtain ar líne: | http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00284/full |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|