SopB activates the Akt-YAP pathway to promote Salmonella survival within B cells
B cells are a target of Salmonella infection, allowing bacteria survival without inducing pyroptosis. This event is due to downregulation of Nlrc4 expression and lack of inflammasome complex activation, which impairs the secretion of IL-1β. YAP phosphorylation is required for downregulation of Nlrc4...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis Group
2018-12-01
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| Seri Bilgileri: | Virulence |
| Konular: | |
| Online Erişim: | http://dx.doi.org/10.1080/21505594.2018.1509664 |
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