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Bidirectional association between zinc and liver cirrhosis: evidence from mendelian randomization and clinical validation

BackgroundIt remains unclear whether low blood zinc levels in cirrhosis patients are a cause or a consequence of the disease.MethodsSeven blood metals (calcium, iron, magnesium, phosphorus, copper, selenium, zinc) were assessed using two-sample Mendelian randomization (MR). We performed reverse MR a...

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Kaydedildi:
Asıl Yazarlar: Liu-dan Liang, Ying Yang, Qi-wen Huang, Chen-yi Huang, Bing-fang Lu, Jian-nan Lv, Wei Wei, Ying Li, Hao Wang, Hong-ling Yuan, Qian Li, Ji-ze Huang, Li Li, Mei-jin Huang, Feng-Lian Deng, Li-mei Liang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2026-07-01
Seri Bilgileri:Frontiers in Genetics
Konular:
calcium
liver cirrhosis
mendelian randomization
metal elements
zinc
Online Erişim:https://www.frontiersin.org/articles/10.3389/fgene.2026.1833546/full
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