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Role of the ubiquitin-proteasome system in the sarcopenic-like phenotype induced by CCL5/RANTES

Sarcopenia is characterized by reduced muscle strength and mass and a decline in muscle fiber diameter and amount of sarcomeric proteins. Sarcopenia involves the activation of the ubiquitin-proteasome system (UPS). MuRF-1 and atrogin-1 are E3 ubiquitin ligases belonging to UPS, leading to proteolys...

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Principais autores: Sabrina Conejeros-Lillo, Francisco Aguirre, Daniel Cabrera, Felipe Simon, Luis Peñailillo, Claudio Cabello-Verrugio
Format: Artigo
Sprog:Inglês
Udgivet: PAGEPress Publications 2024-02-01
Serier:European Journal of Translational Myology
Fag:
Irisin
saliva
serum
muscle
physical exercise
Online adgang:https://www.pagepressjournals.org/index.php/bam/article/view/12249
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