Can platelet to neutrophil ratio (PNR) serve as a viable alternative tool for monitoring sickle cell disease patients on hydroxyurea in low income countries?

Abstract Quantification of foetal haemoglobin (HbF) via high-performance liquid chromatography (HPLC) remains a critical parameter for monitoring therapeutic response to hydroxyurea (HU) in patients with sickle cell disease (SCD). However, its routine application is constrained in low-income setting...

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Hlavní autoři:	Efobi Chilota Chibuife, Nri-Ezedi Chisom Adaobi, Franklin Odini, Habib Darbari Deepika, Nana-Bilkisu Habib, Campbell Andrew
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-12-01
Edice:	Annals of Hematology
Témata:	Sickle cell disease Hydroxyurea Platelet-to-neutrophil ratio Foetal haemoglobin Low-resource settings
On-line přístup:	https://doi.org/10.1007/s00277-025-06598-2
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