Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization

Abstract HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Studies have shown that the association of Nef with the inner leaflet of the plasma membrane and with endocytic and perinuclear vesicles is essential for most activities of Nef. Using purified recombinant proteins in pul...

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Detalhes bibliográficos

Principais autores:	Alexandra Boeske, Melanie Schwarten, Peixiang Ma, Markus Tusche, Jessica Mötter, Christina Möller, Philipp Neudecker, Silke Hoffmann, Dieter Willbold
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2017-07-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-017-06319-4
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