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Overexpression of estrogen receptor α increases hepatic cholesterogenesis, leading to biliary hypersecretion in mice

We explored whether there is an “estrogen-ERα-SREBP-2” (for estrogen-estrogen receptor subtype α-sterol-regulatory element binding protein-2) pathway for regulating hepatic cholesterol biosynthesis in ovariectomized AKR mice treated with 17β-estradial (E2) at 6 μg/day or E2 plus the antiestrogenic a...

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Váldodahkkit: Helen H. Wang, Nezam H. Afdhal, David Q-H. Wang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2006-04-01
Ráidu:Journal of Lipid Research
Fáttát:
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S0022227520332740
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