Gm614 Protects Germinal Center B Cells From Death by Suppressing Caspase-1 Transcription in Lupus-Prone Mice

Only a few signaling pathways have been reported in germinal center (GC) B-cell proliferation and death. In this study, we showed that a novel uncharacterized Gm614 protein is highly expressed in GC B cells from lupus-prone mice. Critically, ablation of this GC B-cell-specific Gm614 promoted GC B-ce...

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Principais autores:	Youdi He, Ruonan Xu, Bing Zhai, Shan Zhou, Xiaoqian Wang, Renxi Wang
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2020-10-01
Serija:	Frontiers in Immunology
Teme:	Gm614 lupus GC B cells cell death caspase-1
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.585726/full
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