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Footprints of a trypanosomatid RNA world: pre-small subunit rRNA processing by spliced leader addition trans-splicing

The addition of a capped mini-exon [spliced leader (SL)] through trans-splicing is essential for the maturation of RNA polymerase (pol) II-transcribed polycistronic pre-mRNAs in all members of the Trypanosomatidae family. This process is an inter-molecular splicing reaction that follows the same bas...

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Auteurs principaux: Mario Gustavo Mayer, Marcos Gonzaga dos Santos, Maria Fernanda Laranjeira da Silva, Lucile Maria Floeter-Winter
Format: Artigo
Langue:Inglês
Publié: Fundação Oswaldo Cruz (FIOCRUZ) 2012-06-01
Collection:Memorias do Instituto Oswaldo Cruz
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Accès en ligne:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000400013&lng=en&tlng=en
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