Adgrg6/Gpr126 is required for compact wall integrity and establishing trabecular identity during cardiac trabeculation

Abstract How adhesion G protein-coupled receptors (aGPCRs) control development remains unclear. aGPCR Adgrg6/Gpr126 has been associated with heart trabeculation. Defects in this process cause cardiomyopathies and cardiac dysfunction. How cardiomyocytes attain trabecular identity is poorly understood...

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Hlavní autoři:	Swati Srivastava, Felix Gunawan, Silvia Vergarajauregui, Alessandra Gentile, Miriam Angeloni, Sarah C. Petersen, Stefan Günther, Fulvia Ferrazzi, Didier Y. R. Stainier, Felix B. Engel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-02-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-026-69292-5
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!