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A NOVEL IN VITRO BONE MARROW NICHE PLATFORM FOR INVESTIGATING THERAPEUTIC STRATEGIES FOR ACUTE LEUKEMIAS

Aims: Acute lymphoblastic leukemia (ALL), the most prevalent childhood cancer, disrupts the hematopoietic bone marrow (BM) niche, a specialized microenvironment that supports normal hematopoiesis. During ALL development, this niche undergoes remodeling and reprogramming to support tumor growth, hind...

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Autors principals: DP Echevarria, MLP Bueno, I Santos, NG Amôr, FM Roversi, AN Bruno, STO Saad
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2024-10-01
Col·lecció:Hematology, Transfusion and Cell Therapy
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2531137924009192
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