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An HPLC-SEC-based rapid quantification method for vesicular stomatitis virus particles to facilitate process development

Virus particle (VP) quantification plays a pivotal role in the development of production processes of VPs for virus-based therapies. The yield based on total VP count serves as a process performance indicator for evaluating process efficiency and consistency. Here, a label-free particle quantificati...

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Bibliografische Detailangaben
Hauptverfasser: Adrian Schimek, Judy K.M. Ng, Ioannes Basbas, Fabian Martin, Dongyue Xin, David Saleh, Jürgen Hubbuch
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-06-01
Schriftenreihe:Molecular Therapy: Methods & Clinical Development
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2329050124000688
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