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KLF2 Inhibits Chicken Preadipocyte Differentiation at Least in Part via Directly Repressing PPARγ Transcript Variant 1 Expression

Peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulatory factor of preadipocyte differentiation. As a result of alternative splicing and alternative promoter usage, PPARγ gene generates multiple transcript variants encoding two protein isoforms. Krüppel-like factor 2 (KLF2)...

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Principais autores: Tingting Cui, Jiaxin Huang, Yingning Sun, Bolin Ning, Fang Mu, Xin You, Yaqi Guo, Hui Li, Ning Wang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-02-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
KLF2
PPARγ
promoter
chicken
preadipocyte differentiation
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2021.627102/full
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