Machine learning–derived genetic risk scores identify IL21 as a predictor of response to omalizumab and dupilumab in asthma
RationaleGenetic risk scores (GRS) of Th1/2/17-related loci may be associated with response to biologics. We leveraged previously published machine learning-derived GRSs associated with plasma proteins from the INTERVAL/UK-Biobank study.MethodsWe assessed 42 Th1/2/17-related GRSs and SNPs for associ...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2025-10-01
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| Serie: | Frontiers in Allergy |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/falgy.2025.1670783/full |
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