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HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication.

Hepatitis C virus (HCV) induces autophagy to promote its replication, including its RNA replication, which can take place on double-membrane vesicles known as autophagosomes. However, how HCV induces the biogenesis of autophagosomes and how HCV RNA replication complex may be assembled on autophagoso...

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Detalhes bibliográficos
Principais autores: Linya Wang, Ja Yeon Kim, Helene Minyi Liu, Michael M C Lai, Jing-Hsiung James Ou
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-09-01
coleção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC5621699?pdf=render
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