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Study of the issues of maintaining stability of poloxamer-based systems during autoclaving

Introduction. Parenteral and ophthalmic in situ systems must be sterile. The selection of sterilization method is a key step in the development of sterile stimuli-sensitive systems, as an inappropriate method can lead to the degradation of the gel-forming polymer and the API, resulting in a loss of...

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Autori principali: E. O. Bakhrushina, A. M. Afonina, V. S. Pyzhov, I. B. Mikhel
Natura: Artigo
Lingua:Russo
Pubblicazione: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2025-12-01
Serie:Разработка и регистрация лекарственных средств
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Accesso online:https://www.pharmjournal.ru/jour/article/view/2192
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