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Clinical characteristics of endometrial cancers with microsatellite instability-high and BRCA1/2 mutations

ObjectiveThe purpose of this study was to identify the clinical features of endometrial cancers (EC) with microsatellite instability-high (MSI-H) and BRCA1/2 mutations (BRCAm).MethodsWe selected patients diagnosed with EC who were MSI-H from the Affiliated Hospital of Qingdao University between Marc...

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Principais autores: Yuping Shan, Yan Wang, Liying Huang, Guangqi Li, Zhumei Cui, Xiaoming Xing, Guangjie Yin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-12-01
Serier:Frontiers in Oncology
Fag:
BRCA1
BRCA2
endometrial neoplasms
homologous recombination deficiency
microsatellite instability
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2025.1685642/full
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