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The Phenoxazine Derivative Phx-1 Suppresses IgE-Mediated Degranulation in Rat Basophilic Leukemia RBL-2H3 Cells
Antigen-induced aggregation of the high affinity IgE receptor (FcεRI) on mast cells induces degranulation to release chemical mediators, leading to acute allergic inflammation. We have demonstrated that the treatment of rat mast cells, RBL-2H3, with a phenoxazine derivative Phx-1 (2-amino-4,4α-dihyd...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2004-01-01
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| Col·lecció: | Journal of Pharmacological Sciences |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S1347861319325010 |
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