Structural basis of the activation of PPARγ by the plasticizer metabolites MEHP and MINCH

Di-2-ethylhexyl phthalate (DEHP) and its substitute 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH) are widely used as plasticizers but may have adverse health effects. Via hydrolysis of one of the two ester bonds in the human body, DEHP and DINCH form the monoesters MEHP and MINCH, respe...

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Үндсэн зохиолчид:	Abibe Useini, Felipe Engelberger, Georg Künze, Norbert Sträter
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2023-03-01
Цуврал:	Environment International
Нөхцлүүд:	Plasticizers DEHP DINCH Peroxisome proliferator-activated receptor γ (PPARγ) Endocrine disruption Structural biology
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0160412023000958
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!