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Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.

mRNA translation into proteins is highly regulated, but the role of mRNA isoforms, noncoding RNAs (ncRNAs), and genetic variants remains poorly understood. mRNA levels on polysomes have been shown to correlate well with expressed protein levels, pointing to polysomal loading as a critical factor. To...

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主要な著者: Roshan Mascarenhas, Maciej Pietrzak, Ryan M Smith, Amy Webb, Danxin Wang, Audrey C Papp, Julia K Pinsonneault, Michal Seweryn, Grzegorz Rempala, Wolfgang Sadee
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2015-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC4558023?pdf=render
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