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Presynaptic Release-Regulating Alpha2 Autoreceptors: Potential Molecular Target for Ellagic Acid Nutraceutical Properties

Polyphenol ellagic acid (EA) possesses antioxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and cardio protection activities, making it an interesting multi-targeting profile. EA also controls the central nervous system (CNS), since it was proven to reduce the immobility time of mice in...

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Principais autores: Isabella Romeo, Giulia Vallarino, Federica Turrini, Alessandra Roggeri, Guendalina Olivero, Raffaella Boggia, Stefano Alcaro, Giosuè Costa, Anna Pittaluga
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-11-01
Serier:Antioxidants
Fag:
pomegranate tannins
ellagic acid
molecular modelling
α<sub>2</sub>-adrenoreceptors
α<sub>2</sub>-ARs
molecular dynamic simulations
Online adgang:https://www.mdpi.com/2076-3921/10/11/1759
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